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Description

Consistently, HIF1A also promotes GSH synthesis through transcriptional activation of GCLM and SLC7A11 , and pharmacological inhibition of SLC7A11 with erastin or sorafenib exacerbates cuproptosis 177,178

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When in excess, these highly reactive chemicals can damage cells by reacting with cellular structures and DNA, a process termed oxidative stress

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Hunter JE, Zhang J, Kris-Etherton PM (2010) Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids: a systematic review

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This showed a strong link between coffee and myeloma, with a 2.72 odds ratio for coffee drinkers

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